Increased Urinary β 2 -Microglobulin in Cadmium Exposure: Dose-Effect Relationship and Biological Significance of β 2 -Microglobulin

Increased urinary beta 2-microglobulin in cadmium exposure: dose-effect relationship and biological significance of beta 2-microglobulin.

A study on the general population from both cadmium-polluted and control areas and on cadmium alloy workers indicates that beta 2-MG in urine is very closely correlated with aging, but it indicates an association with cadmium exposure. However, the age factor is stronger than cadmium exposre in both polluted and control areas among persons without clinical proteinuria. On the other hand, cadmiu...

The Mhc to 2-microglobulin Β Primordial Linkage Of

Unique Effect of Cu(II) in the Metal-Induced Amyloid Formation of β-2-Microglobulin

β-2-Microglobulin (β2m) forms amyloid fibrils in the joints of patients undergoing hemodialysis treatment as a result of kidney failure. In the presence of stoichiometric amounts of Cu(II), β2m self-associates into discrete oligomeric species, including dimers, tetramers, and hexamers, before ultimately forming amyloid fibrils that contain no copper. To improve our understanding of whether Cu(I...

urinary beta 2-microglobulin as a prognostic marker in children with pyelonephritis running title: beta 2-microglobulin a prognostic marker

background urinary tract infection (uti) is common in children. uti with or without vesico-ureteral reflux (vur) may result in renal scarring. severe renal scarring impairs renal function and may result in hypertension, renal insufficiency, and end stage renal disease requiring dialyses or transplantation. beta 2 micro-globulin (ß2mg) is a low molecular weight protein freely filtered by the glo...

Daudi Cells - Microglobulin - Defective 2 β Presentation in Class I HLA Folding and Antigen